Table 2.

RNA-Seq data of HuR target genes. A549 cells were transiently transfected with 50 nM of either synthetic miR-146a or a non-targeting miRNA. Fold changes relative to the control were determined by calculating the average of the biological replicates for each gene. The role that each HuR target gene plays in cancer is also displayed.

HuR Target mRNA	Relative Fold Change	Cancer Traits
CCL2	−4.365	Inflammation, angiogenesis
COX-2	−1.798	Inflammation, angiogenesis
Cyclin E1	−1.474	Proliferation
Cyclin A2	−1.204	Proliferation
Cyclin B1	−1.469	Proliferation
eIF4E	−1.144	Proliferation, survival
BCL-2	−1.791	Survival
Mdm-2	−1.448	Survival
HIF-1⍺	−1.377	Angiogenesis, survival
VEGF	−1.145	Angiogenesis, proliferation