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. 2019 Nov 11;176(Suppl 1):S247–S296. doi: 10.1111/bph.14751
Nomenclature http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1800 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1801 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1802
Common abbreviation InsR IGF1R IRR
HGNC, UniProt https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:6091, http://www.uniprot.org/uniprot/P06213 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:5465, http://www.uniprot.org/uniprot/P08069 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:6093, http://www.uniprot.org/uniprot/P14616
EC number http://www.genome.jp/dbget‐bin/www_bget?ec:2.7.10.1 http://www.genome.jp/dbget‐bin/www_bget?ec:2.7.10.1 http://www.genome.jp/dbget‐bin/www_bget?ec:2.7.10.1
Inhibitors http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=7952 (pIC50 8.7) [http://www.ncbi.nlm.nih.gov/pubmed/19778024?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5683 (pIC50 8.7) [http://www.ncbi.nlm.nih.gov/pubmed/19825801?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5683 (pK d 8.1) [http://www.ncbi.nlm.nih.gov/pubmed/22037378?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5048 (pIC50 > 6) [http://www.ncbi.nlm.nih.gov/pubmed/16648580?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5912 (pIC50 4.7) [http://www.ncbi.nlm.nih.gov/pubmed/9075698?dopt=AbstractPlus]
Selective inhibitors http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=8067 (pIC50 9.4) [http://www.ncbi.nlm.nih.gov/pubmed/15050915?dopt=AbstractPlus]
Endogenous agonists http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5012 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:6081, http://www.uniprot.org/uniprot/P01308) http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=4971 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:5464, http://www.uniprot.org/uniprot/P05019), http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=4972 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:5466, http://www.uniprot.org/uniprot/P01344)