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. 2019 Nov 11;176(Suppl 1):S247–S296. doi: 10.1111/bph.14751
Nomenclature http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1812 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1813 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1814
Common abbreviation VEGFR‐1 VEGFR‐2 VEGFR‐3
HGNC, UniProt https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:3763, http://www.uniprot.org/uniprot/P17948 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:6307, http://www.uniprot.org/uniprot/P35968 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:3767, http://www.uniprot.org/uniprot/P35916
EC number http://www.genome.jp/dbget‐bin/www_bget?ec:2.7.10.1 http://www.genome.jp/dbget‐bin/www_bget?ec:2.7.10.1 http://www.genome.jp/dbget‐bin/www_bget?ec:2.7.10.1
Endogenous ligands http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5085 (http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5085, http://www.uniprot.org/uniprot/P15692), http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5086 (http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5086, http://www.uniprot.org/uniprot/P49765) http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5085 (http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5085, http://www.uniprot.org/uniprot/P15692), http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5087 (http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5087, http://www.uniprot.org/uniprot/P49767), http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5089 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:8801, http://www.uniprot.org/uniprot/Q9NRA1) http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5087 (http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5087, http://www.uniprot.org/uniprot/P49767), http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5088 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:3708, http://www.uniprot.org/uniprot/O43915), http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5089 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:8801, http://www.uniprot.org/uniprot/Q9NRA1)
Inhibitors http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5712 (pIC50 8.7) [http://www.ncbi.nlm.nih.gov/pubmed/16891463?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=8189 (pIC50 8.5) [http://www.ncbi.nlm.nih.gov/pubmed/22148921?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5056 (pIC50 8.1) [http://www.ncbi.nlm.nih.gov/pubmed/10882357?dopt=AbstractPlus] http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5887 (pIC50 10.5) [http://www.ncbi.nlm.nih.gov/pubmed/21926191?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5659 (pIC50 9.6) [http://www.ncbi.nlm.nih.gov/pubmed/20869793?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5679 (pIC50 8.2–9.1) [http://www.ncbi.nlm.nih.gov/pubmed/23098265?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5664 (pK d 9) [http://www.ncbi.nlm.nih.gov/pubmed/22037378?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=7944 (pIC50 8.8) [http://www.ncbi.nlm.nih.gov/pubmed/17575237?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5660 (pK d 8.6) [http://www.ncbi.nlm.nih.gov/pubmed/22037378?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=7886 (pIC50 8.3) [http://www.ncbi.nlm.nih.gov/pubmed/21028894?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5659 (pK d 8.2) [http://www.ncbi.nlm.nih.gov/pubmed/22037378?dopt=AbstractPlus] http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=7944 (pIC50 8.1) [http://www.ncbi.nlm.nih.gov/pubmed/17575237?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5713 (pIC50 8.1) [http://www.ncbi.nlm.nih.gov/pubmed/20570526?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5936 (pIC50 7.9) [http://www.ncbi.nlm.nih.gov/pubmed/18559524?dopt=AbstractPlus]
Sub/family‐selective inhibitors http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5698 (pIC50 8) [http://www.ncbi.nlm.nih.gov/pubmed/18620382?dopt=AbstractPlus] http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5698 (pK d 7.8) [http://www.ncbi.nlm.nih.gov/pubmed/22037378?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5698 (pIC50 7.5) [http://www.ncbi.nlm.nih.gov/pubmed/18620382?dopt=AbstractPlus] http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5698 (pIC50 7.3) [http://www.ncbi.nlm.nih.gov/pubmed/18620382?dopt=AbstractPlus]
Antibodies http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=7390 (Antagonist) (pIC50 9) [http://www.ncbi.nlm.nih.gov/pubmed/12917408?dopt=AbstractPlus]