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. 2019 Nov 11;176(Suppl 1):S247–S296. doi: 10.1111/bph.14751
Nomenclature http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1881 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1882 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1883 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1884 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1885 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1886 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1887
Systematic nomenclature TNFRSF11A TNFRSF11B TNFRSF25 TNFRSF12A TNFRSF13B TNFRSF13C TNFRSF14
Common abbreviation RANK OPG DR3 BAFF‐R HVEM
HGNC, UniProt https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11908, http://www.uniprot.org/uniprot/Q9Y6Q6 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11909, http://www.uniprot.org/uniprot/O00300 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11910, http://www.uniprot.org/uniprot/Q93038 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:18152, http://www.uniprot.org/uniprot/Q9NP84 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:18153, http://www.uniprot.org/uniprot/O14836 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:17755, http://www.uniprot.org/uniprot/Q96RJ3 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11912, http://www.uniprot.org/uniprot/Q92956
Adaptor proteins TRAF1, TRAF2, TRAF3, TRAF5, TRAF6 TRADD TRAF1, TRAF2, TRAF3 TRAF2, TRAF5, TRAF6 TRAF3 TRAF2, TRAF3, TRAF5
Endogenous ligands http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5066 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11926, http://www.uniprot.org/uniprot/O14788) http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5071 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11931, http://www.uniprot.org/uniprot/O95150) http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5067 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11927, http://www.uniprot.org/uniprot/O43508) http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5068 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11928, http://www.uniprot.org/uniprot/O75888), http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5069 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11929, http://www.uniprot.org/uniprot/Q9Y275) http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5069 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11929, http://www.uniprot.org/uniprot/Q9Y275) http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=4891 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:21087, http://www.uniprot.org/uniprot/Q7Z6A9), http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5070 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11930, http://www.uniprot.org/uniprot/O43557), http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5064 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:6709, http://www.uniprot.org/uniprot/P01374)
Comments Acts as a decoy receptor for http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5066 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11926, http://www.uniprot.org/uniprot/O14788) and possibly for http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5065 (https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:11925, http://www.uniprot.org/uniprot/P50591). The only known TNFSF ligand for DR3 is TNF‐like protein 1A (TL1A) [http://www.ncbi.nlm.nih.gov/pubmed/22612445?dopt=AbstractPlus].