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. 2019 Nov 11;176(Suppl 1):S297–S396. doi: 10.1111/bph.14752
Nomenclature http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2467 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2464 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2466
Common abbreviation GABA‐T SSADH
HGNC, UniProt https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:412, http://www.uniprot.org/uniprot/P49189 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:23, http://www.uniprot.org/uniprot/P80404 https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:408, http://www.uniprot.org/uniprot/P51649
EC number http://www.genome.jp/dbget‐bin/www_bget?ec:1.2.1.19: http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6606 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2451 + H2O = http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1067 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=4487 + H+ http://www.genome.jp/dbget‐bin/www_bget?ec:1.2.1.47: http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6604 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2451 + H2O = http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6605 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=3041 + 2H+ http://www.genome.jp/dbget‐bin/www_bget?ec:1.2.1.3: an aldehyde + H2O + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2451 = a carboxylate + 2H+ + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=4487 http://www.genome.jp/dbget‐bin/www_bget?ec:2.6.1.19: http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1067 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=3636 = http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1369 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6608 http://www.genome.jp/dbget‐bin/www_bget?ec:2.6.1.22: http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6610 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=3636 = http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6611 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1369 http://www.genome.jp/dbget‐bin/www_bget?ec:1.2.1.24: http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6608 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2451 + H2O = http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=3637 + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=4487 + 2H+ 4‐hydroxy‐trans‐2‐nonenal + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2451 + H2O = 4‐hydroxy‐trans‐2‐nonenoate + http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=4487 + 2H+
Cofactors http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2451 http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5249 http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2451 [http://www.ncbi.nlm.nih.gov/pubmed/22677141?dopt=AbstractPlus]
Inhibitors http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=4821 (Irreversible inhibition) (pK i 3.1) [http://www.ncbi.nlm.nih.gov/pubmed/856582?dopt=AbstractPlus, http://www.ncbi.nlm.nih.gov/pubmed/22168767?dopt=AbstractPlus] http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=8841 (pIC50 6.5) [http://www.ncbi.nlm.nih.gov/pubmed/16290145?dopt=AbstractPlus]