Nomenclature	http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=522	http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=523	http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=524	http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=525	http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=526	http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=527
Common abbreviation	THIK2	THIK1	TASK5	TALK1	TALK2	TRESK
HGNC, UniProt	https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:6274, http://www.uniprot.org/uniprot/Q9HB15	https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:6275, http://www.uniprot.org/uniprot/Q9HB14	https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:13814, http://www.uniprot.org/uniprot/Q9H427	https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:14464, http://www.uniprot.org/uniprot/Q96T55	https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:14465, http://www.uniprot.org/uniprot/Q96T54	https://www.genenames.org/data/gene‐symbol‐report/#!/hgnc_id/HGNC:19439, http://www.uniprot.org/uniprot/Q7Z418
Endogenous inhibitors	–	–	–	–	–	http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2391 (studied at 10‐50 μM) [http://www.ncbi.nlm.nih.gov/pubmed/12754259?dopt=AbstractPlus]
Inhibitors	–	http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2401 (studied at 5 mM) [http://www.ncbi.nlm.nih.gov/pubmed/25148687?dopt=AbstractPlus]	–	–	–	–
Functional Characteristics	Does not function as a homodimer [http://www.ncbi.nlm.nih.gov/pubmed/11060316?dopt=AbstractPlus] but can form a functional heterodimer with K2P13 [http://www.ncbi.nlm.nih.gov/pubmed/25148687?dopt=AbstractPlus].	Background current	Unknown	Background current	Background current	Background current
Comments	–	Forms a heterodimer with K2P12 [http://www.ncbi.nlm.nih.gov/pubmed/25148687?dopt=AbstractPlus].	–	K2P16.1 current is increased by alkaline pHo with a pKa of 7.8 [http://www.ncbi.nlm.nih.gov/pubmed/14985088?dopt=AbstractPlus].	K2P17.1 current is increased by alkaline pHo with a pKa of 8.8 [http://www.ncbi.nlm.nih.gov/pubmed/14985088?dopt=AbstractPlus].	A frame‐shift mutation (F139WfsX24) in the KCNK18 gene, is associated with migraine with aura in humans [http://www.ncbi.nlm.nih.gov/pubmed/20871611?dopt=AbstractPlus].