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Diabetes induced Aβ1-42 accumulation and downregulated the expression of BDNF and MAP2. (A-B) The immunohistochemical staining of Aβ1-42 and BDNF in CA1, CA3, and PFC of the hippocampus. (C) The immunofluorescence staining of MAP2 in CA1, CA3, and PFC. CON: control, PFC: prefrontal cortex, CA1: cornu ammon1, and CA3: cornu ammon3Scale bar = 50 μm, and N = 4.
