Table 1.
Frequencies of class I HLA-A alleles in patients with Buerger's disease and controls
| HLA-A | Patient’s alleles (n = 55) | Control’s alleles (n = 500) | OR | CI*95% | P-Value | ||
|---|---|---|---|---|---|---|---|
| N | (%) | N | (%) | ||||
| HLA-A*01 | 11 | 20.0 | 58 | 11.6 | 1.905 | 0.932-3.895 | 0.073 |
| HLA-A*02 | 17 | 30.9 | 105 | 21.0 | 1.683 | 0.913-3.101 | 0.092 |
| HLA-A*03 | 22 | 40.0 | 55 | 11.0 | 5.394 | 2.937-9.906 | <0.001 |
| HLA-A*11 | 15 | 27.3 | 55 | 11.0 | 3.034 | 1.574-5.848 | 0.001 |
| HLA-A*24 | 20 | 36.4 | 50 | 10.0 | 5.143 | 2.760-9.582 | <0.001 |
| HLA-A*25 | 2 | 3.6 | 0 | 0.0 | ∞ | - | 0.010 |
| HLA-A*26 | 3 | 5.4 | 33 | 6.6 | 0.816 | 0.242-2.755 | 0.999 |
| HLA-A*29 | 3 | 5.4 | 14 | 2.8 | 2.003 | -0.557-7.198 | 0.232 |
| HLA-A*30 | 0 | 0.0 | 27 | 5.4 | 0 | - | 0.097 |
| HLA-A*31 | 6 | 10.9 | 14 | 2.8 | 4.251 | 1.563-11.560 | 0.002 |
| HLA-A*32 | 4 | 7.3 | 16 | 3.2 | 2.373 | 0.764-7.367 | 0.126 |
| HLA-A*33 | 1 | 1.8 | 14 | 2.8 | 0.643 | 0.083-4.984 | 0.999 |
| HLA-A*66 | 2 | 3.6 | 0 | 0.0 | ∞ | - | 0.010 |
| HLA-A*68 | 3 | 5.4 | 29 | 5.8 | 0.937 | 0.276-3.182 | 0.999 |
| HLA-A*69 | 1 | 1.8 | 3 | 6.0 | 3.068 | 0.314-30.010 | 0.342 |
*
CI: confidence interval, OR: odds ratio