Table 2.
Frequencies of class I HLA-B alleles in the TAO patients and controls
| HLA-B | Patient’s alleles (n = 55) | Control’s alleles (n = 500) | OR | CI* 95% | P-Value | ||
|---|---|---|---|---|---|---|---|
| N | (%) | N | (%) | ||||
| HLA-B*07 | 8 | 14.5 | 22 | 4.4 | 3.698 | 1.560-8.765 | 0.002 |
| HLA-B*08 | 0 | 0.0 | 15 | 3.0 | 0 | - | 0.205 |
| HLA-B*13 | 3 | 5.5 | 30 | 6.0 | 0.904 | 0.267-3.064 | 0.583 |
| HLA-B*14 | 1 | 1.8 | 20 | 4.0 | 0.444 | 0.058-3.377 | 0.365 |
| HLA-B*15 | 6 | 10.9 | 15 | 2.9 | 3.959 | 1.469-10.669 | 0.004 |
| HLA-B*18 | 8 | 14.5 | 33 | 6.5 | 2.409 | 1.052-5.516 | 0.032 |
| HLA-B*27 | 6 | 10.9 | 9 | 1.8 | 6.680 | 2.282-19.552 | <0.001 |
| HLA-B*35 | 18 | 32.7 | 82 | 16.4 | 2.480 | 1.346-4.568 | 0.003 |
| HLA-B*37 | 1 | 1.8 | 7 | 1.4 | 1.304 | 0.157-10.801 | 0.568 |
| HLA-B*38 | 9 | 16.4 | 31 | 6.1 | 2.960 | 1.328-6.598 | 0.006 |
| HLA-B*39 | 1 | 1.8 | 11 | 2.2 | 0.823 | 0.104-6.500 | 0.663 |
| HLA-B*40 | 6 | 10.9 | 22 | 4.3 | 2.660 | 1.030-6.875 | 0.036 |
| HLA-B*41 | 1 | 1.8 | 25 | 5.1 | 0.352 | 0.047-2.648 | 0.249 |
| HLA-B*44 | 7 | 12.7 | 21 | 4.3 | 3.326 | 1.345-8.226 | 0.006 |
| HLA-B*45 | 0 | 0.0 | 10 | 0.2 | 0 | - | 0.349 |
| HLA-B*46 | 0 | 0.0 | 5 | 0.1 | 0 | - | 0.592 |
| HLA-B*49 | 4 | 7.3 | 23 | 4.7 | 1.627 | 0.541-4.888 | 0.274 |
| HLA-B*50 | 6 | 10.9 | 27 | 5.4 | 2.145 | 0.844-5.449 | 0.101 |
| HLA-B*51 | 14 | 25.5 | 46 | 9.2 | 3.370 | 1.710-6.641 | <0.001 |
| HLA-B*52 | 5 | 9.1 | 19 | 3.8 | 2.532 | 0.906-7.072 | 0.067 |
| HLA-B*53 | 0 | 0.0 | 7 | 1.4 | 0 | - | 0.480 |
| HLA-B*55 | 2 | 3.6 | 18 | 3.6 | 1.010 | 0.228-4.475 | 0.608 |
| HLA-B*57 | 1 | 1.8 | 12 | 2.3 | 0.753 | 0.096-5.904 | 0.625 |
| HLA-B*58 | 1 | 1.8 | 10 | 0.2 | 0.907 | 0.114-7.225 | 0.701 |
*
CI: confidence interval, OR: odds ratio