Table 3.
Frequencies of class II HLA-DR alleles in the TAO patients and controls
| HLA-DR | Patient’s alleles (n = 55) | Control’s alleles (n = 500) | OR | CI* 95% | P-Value | ||
|---|---|---|---|---|---|---|---|
| N | (%) | N | (%) | ||||
| HLA-DRB1*01 | 3 | 5.4 | 38 | 7.6 | 0.701 | 0.209-2.352 | 0.787 |
| HLA-DRB1*03 | 10 | 18.2 | 44 | 8.8 | 2.303 | 1.086-4.884 | 0.026 |
| HLA-DRB1*04 | 31 | 56.4 | 63 | 12.6 | 8.960 | 4.943-16.240 | <0.001 |
| HLA-DRB1*07 | 8 | 14.5 | 75 | 15.0 | 0.965 | 0.438-2.123 | 0.929 |
| HLA-DRB1*08 | 1 | 1.8 | 0 | 0.0 | ∞ | - | 0.099 |
| HLA-DRB1*09 | 1 | 1.8 | 6 | 1.2 | 1.525 | 0.180-12.902 | 0.520 |
| HLA-DRB1*10 | 3 | 5.4 | 0 | 0.0 | ∞ | - | 0.001 |
| HLA-DRB1*11 | 8 | 14.5 | 75 | 15.0 | 0.965 | 0.438-2.123 | 0.929 |
| HLA-DRB1*12 | 1 | 1.8 | 0 | 0.0 | ∞ | - | 0.099 |
| HLA-DRB1*13 | 9 | 16.4 | 81 | 16.2 | 1.012 | 0.477-2.149 | 0.975 |
| HLA-DRB1*14 | 5 | 9.1 | 13 | 2.6 | 3.746 | 1.283-10.940 | 0.010 |
| HLA-DRB1*15 | 19 | 34.5 | 100 | 20.0 | 2.111 | 1.162-3.837 | 0.013 |
| HLA-DRB1*16 | 11 | 20.0 | 6 | 1.2 | 20.583 | 7.265-58.317 | <0.001 |
*
CI: confidence interval, OR: odds ratio