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Designed Anti-mHtt and Anti-Ubc9 peptides mapped on the 3D model of RHES-GTP. The RHES-GTP model is represented by its solvent accessible surface area. (A) Peptides Anti-mHtt_1 and Anti-mHtt_2 are coloured yellow. (B) Peptides Anti-Ubc9_1 and Anti-Ubc9_2 are coloured green. In both panels, the rest of the RHES model is coloured as in Fig. 1B. Htt, huntingtin; RHES, Ras Homolog Enriched in Striatum; Ubc9, ubiquitin carrier protein 9; GTP, guanosine triphosphate.
