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. 2019 Nov 1;26(11):959–969. doi: 10.5551/jat.47324

Table 3. Additional prognostic information provided by big endothelin-1 level beyond SSII.

C-index (95% CI) P-value NRI (95% CI) P-value IDI (95% CI) P-value
SSII 0.715 (0.697–0.734) Reference Reference Reference
SSII + big ET-1 0.723 (0.704–0.742) 0.029 0.304 (0.229–0.378) < 0.001 0.009 (0.006–0.012) < 0.001