Table 3.

Brain regions exhibiting significant correlations between total TEI scale score and MD value

Included gray matter areas* (number of significant voxels in the left and right side of each anatomical area)	x	y	z	TFCE value	Corrected p value (FWE)	Cluster size (voxel)	Semi-partial correlation coefficients**
Negative correlation
Insula (R:73)/Pallidum (R:340)/Putamen (R:432)/Thalamus (R:2)/	31.5	−4.5	4.5	994	0.010	999	−0.112
Positive correlation
Middle cingulum (L:13)/Inferior frontal operculum (L:70)/Middle frontal other areas (L:2)/Superior frontal medial area (L:4)/Superior frontal other areas (L:249)/Insula (L:25)/Paracentral lobule (L:5)/Precentral gyrus (L:1)/Rolandic operculum (L:47)/Supplemental motor area (L:548)/	−9	9	55.5	951	0.012	1597	0.073
Anterior cingulum (L:11)/Middle cingulum (L:15)/Inferior frontal orbital area (L:5)/Inferior frontal triangular (L:55)/Middle frontal other areas (L:12)/Superior frontal medial area (L:157)/Superior frontal other areas (L:64)/	−30	39	1.5	809	0.029	816	0.063

^*The anatomical regions of the gray matter were labeled based on the WFU PickAtlas Tool (http://www.fmri.wfubmc.edu/cms/software#PickAtlas/) (Maldjian et al., 2003, 2004) and on the PickAtlas automated anatomical labeling atlas option (Tzourio-Mazoyer et al., 2002). Temporal pole areas included all subregions in the areas of this atlas.

^**Semi-partial correlation coefficients of the associations with mean MD values of significant clusters. Note any correlation coefficients in the significant areas of whole brain analyses do not reflect true effect size due to overfitting depending on factors such as sample size and the number of multiple comparisons.