Figure 2.

PRISMA flow diagram of literature search methodology for publications examining the effectiveness of potential fertility protective agents. Search results, study screening, and study inclusion, following a review of the literature carried out using PRISMA guidelines (Moher et al., 2009). Selected key words were searched in PubMed until March 2019, with 24 additional references identified through other sources, resulting in examination of 1357 papers. After the analysis of all publications for the inclusion and exclusion criteria, 40 articles from the initial search were used in this review.