Table 1.

Socio-demographic, lifestyle and health characteristics of the sample at baseline, for women and men separately^a

	Women (N = 3374)	Men (N = 2243)
	%	%	pd
Centre
Bordeaux	23.8	23.1
Dijon	57.4	53.7
Montpellier	18.8	23.3	0.0002
Age (years) (median, IQR)	73.2 (69.4–77.2)	72.5 (69.2–76.9)	0.004
Education (>5 years)	75.3	78.6	0.005
Living alone	48.2	13.9	<0.0001
Smoking
Never	81.9	31.3
Former	14.4	60.6
Current	3.7	8.1	<0.0001
Alcohol consumption (g/day) (median, IQR)	4.5 (0–11.0)	19.2 (2.3–30.5)	<0.0001
BMI (kg/m2) (mean, SD)	25.4 (4.3)	26.2 (3.4)	<0.0001
Chronic diseases
Hypertension	73.9	64.1	<0.0001
Hypercholesterolemia	39.4	34.2	<0.0001
Diabetes	5.6	9.9	<0.0001
Ischemic disease	11.3	20.7	<0.0001
MMSE score (median, IQR)	28 (27–29)	28 (27–29)	0.29
Visual or hearing impairment	18.8	18.2	0.55
Dependency level
Low (or fully independent)	50.0	69.3
Moderate (mobility restriction only)	42.3	26.0
High (IADL and/or ADL limitation)	7.7	4.7	<0.0001
Anxiolytic consumption	17.2	7.6	<0.0001
Antidepressant consumption	7.0	2.4	<0.0001
APOE ɛ4 carrier	19.3	20.2	0.40
CES-D dimensions (median, IQR)
Somatic affectb	1.7 (0.6–2.9)	1.1 (0.6–2.3)	<0.0001
Depressed affectb	0.8 (0–3.2)	0 (0–0.8)	<0.0001
Positive affectc	3.0 (1–6)	2.0 (0–4)	<0.0001
Interpersonal challenge	0 (0–2)	0 (0–1)	<0.0001
Total CES-D score	9 (4–15)	6 (2–10)	<0.0001
Depressive symptomatology: high (CES-D≥16)	24.3	10.6	<0.0001

^aless than 1% missing values except for alcohol consumption (6.5%)

^bstandardised to 0–12 scale

^creversed so that a high score reflects low positive affect

^dχ² test for categorical variables, Student’s T-test for normally distributed continuous variables and Wilcoxon Test for skewed continuous or ordinal variables