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. 2019 Nov 5;13:494. doi: 10.3389/fncel.2019.00494

TABLE 1.

Sample description for gene polymorphism analysis.

Characteristic CP cases
Control
Total (%) M/F (n) Total (%) M/F (n)
Gestational age
Preterm (<37 weeks) 40 (5.59) 33/7 11 (1.67) 10/1
Term (≥37 weeks) 675 (94.41) 463/212 647 (98.33) 428/219
Total 715 (100) 496/219 658 (100) 438/220
Type of CP
Spastic CP 468 (65.45) 338/130
Non-spastic CP 247 (34.55) 158/89
Total 715 (100) 496/219 658 (100) 438/220
Birth weight
<2500 g 29 (4.06) 20/9 17 (2.58) 13/4
≥2500 g 686 (95.94) 485/201 641 (97.42) 425/216
Total 715 (100) 505/210 658 (100) 438/220
Birth asphyxia
Asphyxia 212 (29.65) 157/55 10 (1.52) 7/3
No Asphyxia 503 (70.35) 339/164 648 (98.48) 431/217
Total 715 (100) 496/219 658 (100) 438/220
Maternal factors
PROM 68 (951) 51/17 24 (3.65) 16/8
No PROM 647 (90.49) 425/202 634 (96.35) 420/214
TPL 57 (7.97) 40/17 33 (5.02) 27/6
No TPL 648 (92.03) 454/196 625 (94.98) 411/214
PIH 27 (3.78) 21/6 8 (1.22) 7/1
No PIH 688 (96.22) 476/212 650 (98.78) 431/219
Complication
With PVL 67 (9.37) 53/14
Without PVL 648 (90.63) 445/203
With HIE 96 (13.45) 71/25
Without HIE 619 (86.55) 421/198
With MR 289 (40.42) 199/90
Without MR 426 (59.58) 297/129

CP, cerebral palsy; M, male; F, female; PVL, periventricular leukomalacia; PROM, premature rupture of membrane; TPL, threatened premature labor; PIH, pregnancy-induced hypertension; HIE, hypoxic ischemic encephalopathy; MR, mental retardation.