TABLE 5.
Allele and genotype frequencies of ATG7 in male CP patient and male controls.
| Gene | Group | Allele frequency | p-Value | OR [95% CI] | Genotype frequency | p-Value | H-W∗ | |||
| rs346078 | C | G | C/C | C/G | G/G | |||||
| CP | 244 (0.278) | 634 (0.722) | 0.423 | 0.916 [0.740–1.135] | 30 (0.068) | 184 (0.419) | 225 (0.513) | 0.541 | ||
| Control | 226 (0.296) | 538 (0.704) | 48 (0.089) | 243 (0.414) | 274 (0.497) | 0.888 | ||||
| rs1470612 | A | G | A/A | A/G | G/G | |||||
| CP | 310 (0.357) | 558 (0.643) | 0.001a | 1.408 [1.141–1.738] | 63 (0.145) | 184 (0.431) | 187 (0.431) | 0.0009b | ||
| Control | 215 (0.283) | 545 (0.717) | 25 (0.066) | 165 (0.434) | 190 (0.500) | 0.171 | ||||
| rs11706903 | A | C | A/A | A/C | C/C | |||||
| CP | 297 (0.344) | 567 (0.656) | 0.010c | 1.318 [1.067–1.628] | 59 (0.137) | 179 (0.414) | 194 (0.449) | 0.017 | ||
| Control | 215 (0.284) | 541 (0.716) | 29 (0.077) | 157 (0.415) | 192 (0.508) | 0.691 | ||||
| rs2606750 | A | G | 1.128 [0.916–1.390] | A/A | A/G | G/G | ||||
| CP | 308 (0.397) | 468 (0.603) | 0.257 | 80 (0.206) | 148 (0.381) | 160 (0.412) | 0.207 | |||
| Control | 266 (0.368) | 456 (0.632) | 57 (0.158) | 152 (0.421) | 152 (0.421) | 0.070 | ||||
| rs2594972 | T | C | T/T | C/T | C/C | |||||
| CP | 398 (0.482) | 428 (0.518) | 0.0001d | 1.515 [1.244–1.848] | 120 (0.291) | 158 (0.383) | 135 (0.327) | <0.0001e | ||
| Control | 298 (0.380) | 486 (0.620) | 60 (0.153)1 | 178 (0.454) | 54 (0.393) | 0.471 | ||||
| rs4684787 | T | C | T/T | C/T | C/C | |||||
| CP | 318 (0.360) | 566 (0.640) | 0.549 | 0.941 [0.769–1.149] | 52 (0.118) | 214 (0.484) | 176 (0.398) | 0.826 | ||
| Control | 285 (0.374) | 477 (0.626) | 49 (0.129) | 187 (0.491) | 145 (0.381) | 0.347 | ||||
aAfter the SNPSpD correction, the p-value is 0.0004; bAfter the SNPSpD correction, the p-value is 0.0036; cAfter the SNPSpD correction, the p-value is 0.040; dAfter the SNPSpD correction, the p-value is 0.0004; eAfter the SNPSpD correction, the p-value is < 0.0001. ∗Hardy–Weinberg equilibrium.