Table 3.

General linear model 1

GLM1 Increase in PANSS positive ~ β0 + β1*ΔBPND + β2*CTQ + β3*[ΔBPND*CTQ]
F		Adjusted R2	p Value vs. constant model
F(20,3) = 6915		0.44	0.002
	Unstandardized coefficients		Standardized coefficients	t	p Value
	β	Std. error	β
Constant (β0)	2.22	1.326		1.674	0.11
ΔBPND (β1)	−0.153	0.07	−0.914	−2.191	0.04
CTQ (β2)	−0.077	0.032	−1.441	−2.38	0.027
ΔBPND × CTQ (β3)	0.007	0.002	1.828	3.405	0.003

ΔBP_ND ventral striatum dopamine release capacity (%), CTQ Childhood Trauma Questionnaire, GLM general linear model

The general linear model including dexamphetamine-induced positive psychotic symptoms as dependent variable was superior to the null-model in predicting symptom scores and providing evidence that the interaction between childhood trauma and mesolimbic dopamine sensitivity (interaction term: ΔBP_ND × CTQ score) was a predictor of dexamphetamine-induced positive psychotic symptoms