Table 1.

Number of SAR data point in large pharmaceutical companies reported in literatures.

Company	# of SAR point	Date	Reference
AstraZeneca	150 million single-shot SAR points, 14 milliona CR SAR points	Up to 2008	(Proffitt, 2008; Muresan et al., 2011)
Boehringer Ingelheim	260 million single-shot SAR points, 7 million CR SAR points	Up to 2011	(Beck, 2012)
Pfizer	0.6 million CR SAR points	Up to 2005	(Paolini et al., 2006)
Johnson & Johnson	30 million SAR points	Up to 2006	(Agrafiotis et al., 2007)

a) This number includes external sources, up to 2012.