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Treatment protocol in management of osteosarcoma of jaws [12]
| A. Definitive Treatment |
| (I) Any T,N0, M0 |
| (a) Low Grade (G1): Surgery with minimum 2 cm of clear margins |
| (b) High Grade (G2–G3): Induction chemotherapy + Surgery ± Post Op radiotherapy |
| (II) Any T, N1, M1 |
| Chemotherapy + surgery |
| B. Salvage treatment for loco-regional relapse |
| (a) Palliative care |
| (b) Chemotherapy/surgery/radiotherapy |
| C. Salvage treatment for metastatic disease |
| (a) Chemotherapy |
| (b) Surgery ± metastatectomy |
