Table 2.
Clinicopathological features of OSCC patients and their relationship with Tyr705-phosphorylated STAT3 expression (n = 68).
| Characteristics | Cases | Tyr705-phosphorylated STAT3 | p value | |
|---|---|---|---|---|
| Higher (≥54%) | Lower (<54%) | |||
| Age (years) | ||||
| <60 | 31 | 17 | 14 | 0.341 |
| ≥60 | 37 | 16 | 21 | |
| Gender | ||||
| Female | 29 | 14 | 15 | 0.572 |
| Male | 39 | 19 | 20 | |
| Drink | ||||
| Yes | 45 | 25 | 20 | 0.105 |
| No | 23 | 8 | 15 | |
| Smoke | ||||
| Yes | 42 | 20 | 22 | 0.849 |
| No | 26 | 13 | 13 | |
| Tumor size | ||||
| T1–T2 | 20 | 6 | 14 | 0.048* |
| T3–T4 | 48 | 27 | 21 | |
| Differentiation | ||||
| Well | 30 | 4 | 26 | <0.000* |
| Moderate | 21 | 14 | 7 | |
| Poor | 17 | 15 | 2 | |
| Clinical stage | ||||
| I–II | 18 | 3 | 15 | 0.002* |
| III–IV | 50 | 30 | 20 | |
| Nodal metastasis | ||||
| Yes | 19 | 14 | 5 | 0.010* |
| No | 49 | 19 | 30 | |
| Recurrence | ||||
| Yes | 13 | 8 | 5 | 0.297 |
| No | 55 | 25 | 30 | |
*
p < 0.05 was regarded as statistically significant in Chi square test.