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. 2019 Nov 5;10:1068. doi: 10.3389/fgene.2019.01068

Table 5.

Quantitative trait loci (QTL) associated with gestation length across all 22,566 sires with gestation length phenotypes*.

BTA Start End No SNP <10-5 Strongest SNP Strongest SNP position + Allele + Allele Freq P-value No genes Candidate gene(s)
2 25703163 25764224 2 rs440124614d 25703163 C 0.977 4.91 x10-6 1 ERICH2
3 98841884 98849329 29 rs209841235a 98847024 T 0.132 1.37 x10-6 0
3 100766422 100777480 3 rs42581438b 100773079 C 0.550 8.16 x10-7 1 MAST2
3 104046559 104266624 6 a 104266624 C 0.988 3.86 x10-6 7 CLDN19
4 94319933 94818120 3 rs479683550a 94818120 T 0.995 7.17 x10-7 10 UBE2H
4 95321764 95321892 8 rs473707947a 95321870 A 0.066 8.50 x10-7 0
7 52922609 53089185 25 rs378423353c 53088085 T 0.126 4.16 x10-8 4 CYSTM1
7 55759705 55833318 2 rs382485411a 55801809 A 0.074 5.83 x10-6 1 ARHGAP26
10 28673906 28888361 28 rs522302467c 28849088 C 0.015 7.46 x10-6 2 AVEN,RYR3
10 41772174 41856602 66 rs210399646a 41814534 C 0.150 1.00 x10-6 0
10 83626502 83634162 2 rs207683997d 83626502 A 0.898 4.48 x10-7 1 SIPA1L1
12 61738949 62374951 6 a 62343825 C 0.990 2.01 x10-6 0
13 40292785 40396496 8 rs209154825c 40362715 T 0.881 1.17 x10-6 1 RALGAPA2
13 59061885 59065514 3 rs209578693c 59064151 T 0.793 9.64 x10-7 1 PMEPA1
14 44492347 48599522 30 rs210147540a 46786108 T 0.968 3.36 x10-7 20 PAG1
18 56165021 56280028 2 rs436362295a 56165021 C 0.016 2.18 x10-6 5 CD37
18 56551941 56711791 9 rs134804275c 56645162 T 0.017 1.23 x10-7 10 MED25
19 25866591 26579664 2 rs455574605a 26440513 A 0.125 1.41 x10-6 5 WSCD1
19 28459429 28642278 3 rs378930477d 28461407 T 0.103 5.12 x10-6 9 CTC1,PFAS,
21 40864588 41148186 23 rs209001772a 40955154 T 0.474 1.76 x10-6 1 ENSBTAG00000027863
22 49840740 49982657 13 rs379946352d 49940652 T 0.974 1.26 x10-7 3 DCAF1,RBM15B,DOCK3
26 20495664 20642095 5 rs382274415a 20604629 A 0.949 4.51 x10-6 5 ABCC2
28 12400473 12409730 5 rs378225261a 12401160 C 0.910 7.44 x10-6 0
28 15704269 15727249 2 rs444722974a 15704269 C 0.005 2.38 x10-7 0

*BTA, Bos taurus autosome number; SNP, name of single nucleotide polymorphism. No SNP <10-5 is the number of SNPs within the QTL with a p-value ≤ 1 × 10-5. P-value is the p-value of strongest SNP association. + Allele is the allele that had a positive SNP effect on gestation length. No of genes is the number of genes in the QTL. If no gene was present in the QTL the nearest functional candidate gene within 250 kb was chosen. aintergenic, bupstream gene variant, cintronic, ddownstream gene variant,gene in which the most significant SNP within the QTL was identified in.