Table 1.
Baseline Patient Characteristics Associated with Fluoroquinolone Prescribing
| Patient characteristics | Academic clinic N = 56 |
Non-academic clinic N = 160 |
|---|---|---|
| Age (years), mean (SD) | 55.9 (14.0) | 53.8 (15.3) |
| Male, n (%) | 9 (16.1) | 15 (9.4) |
| Race, n (%) | ||
| African American | 41 (73.2) | 100 (62.5) |
| Hispanic | 4 (7.1) | 33 (20.6) |
| Caucasian | 8 (14.3) | 18 (11.3) |
| Other | 3 (5.4) | 9 (5.6) |
| Temperature, n (%) | ||
| ≥ 100.4 (°F) | 2 (3.6) | 1 (0.6) |
| White blood cell count (K/mcL), n (%) | ||
| >10.7 | 1 (1.8) | 3 (1.9) |
| Glomerular filtration rate (mL/min), n (%) | ||
| ≥ 60 | 44 (78.6) | 140 (87.5) |
| 15–59 | 11 (19.6) | 20 (12.5) |
| < 15 and/or hemodialysis | 1 (1.8) | 0 (0.0) |
| Failed previous antibiotic therapy, n (%) | 9 (16.1) | 18 (11.3) |
| Fluoroquinolone prescribed, n (%) | ||
| Ciprofloxacin | 36 (64.3) | 136 (85.0) |
| Levofloxacin | 20 (35.7) | 24 (15.0) |
| Duration of therapy (days), mean (SD) | 8.8 (12.0) | 6.5 (5.0) |
| Provider, n (%) | ||
| Attending physician | 14 (25.0) | 127 (79.4) |
| Resident physician | 40 (71.4) | 2 (1.3) |
| Advanced practice provider | 2 (3.6) | 31 (19.4) |
| Indication, inappropriate/total prescriptions (% inappropriate) | ||
| Cystitis/pyelonephritis | 26/31 (83.9) | 125/128 (97.7) |
| Upper respiratory tract infection (bronchitis, sinusitis) | 3/3 (100) | 12/12 (100) |
| Intra-abdominal infection/diverticulitis | 3/3 (100) | 5/8 (62.5) |
| Skin and soft tissue infection | 1/2 (50.0) | 7/9 (77.8) |
| Pneumonia | 6/9 (66.7) | 1/1 (100) |
| Osteomyelitis | 0/5 (0.0) | 0/0 (0.0) |
| Otitis externa | 0/0 (0.0) | 2/2 (100) |
| Chronic obstructive pulmonary disease exacerbation | 2/2 (100) | 0/0 (0.0) |
| Prevention of spontaneous bacterial peritonitis | 0/1 (0.0) | 0/0 (0.0) |