Table 2.
Association of maternal RBC folate concentrations with GDM risk
| Groups | GDM OR (95% CI) | |
|---|---|---|
| Univariate | Multivariate | |
| Quintiles | ||
| Q1 (≤1,053.46) | 1.00 (ref) | 1.00 (ref) |
| Q2 (1,053.46–1,311.47) | 2.31 (1.52, 3.50) | 2.25 (1.47, 3.43) |
| Q3 (1,311.47–1,632.50) | 2.86 (1.91, 4.29) | 2.65 (1.75, 4.02) |
| Q4 (1,632.50–1,962.06) | 2.08 (1.37, 3.18) | 1.78 (1.16, 2.75) |
| Q5 (1,962.06–5,108.11) | 2.64 (1.75, 3.97) | 2.31 (1.51, 3.52) |
| P trend | 3.12 × 10–4 | 0.012 |
| Proposed cutoff (nmol/L) | ||
| <906 | 1.00 (ref) | 1.00 (ref) |
| 906–1,292 | 2.14 (1.19, 3.85) | 2.17 (1.20, 3.95) |
| ≥1,292 | 3.00 (1.71, 5.25) | 2.76 (1.56, 4.89) |
| P trend | <0.001 | <0.001 |
| Per 1‐SD increasea | 1.22 (1.09, 1.37) | 1.16 (1.03, 1.30) |
All values are ORs (95% CIs) and determined by using logistic regression.
Adjusted values were adjusted for maternal age, parity, and BMI at enrollment.
a
ORs and 95% CIs were per 1‐SD increase of log‐transformed RBC folate concentrations.