Table 2. List of up-regulated proteins in AMD group compared with control group.
Accession No. | Gene name | Protein name | Peptides (95%) | Fold change | FDR (%) | Stability ratio | FDR (%) |
P05109 | S10A8 | Protein S100-A8 | 8 | 8.11285 | 0.0363 | 1.16525 | 0.3044 |
Q14118 | DAG1 | Dystroglycan | 2 | 7.144 | 0.5497 | 0.9954 | 0.4929 |
P01876 | IGHA1 | Ig alpha-1 chain C region | 30 | 6.36825 | 0.2284 | 0.8273 | 0.5461 |
P07451 | CAH3 | Carbonic anhydrase 3 | 3 | 5.37175 | 0.0713 | 1.05845 | 0.8471 |
P02763 | A1AG1 | Alpha-1-acid glycoprotein | 44 | 5.3211 | 0.3553 | 1.0333 | 0.6994 |
P06727 | APOA4 | Apolipoprotein A-IV | 47 | 4.9457 | 0.0001 | 1.1966 | 0.3151 |
P02788 | TRFL | Lactotransferrin | 25 | 4.43605 | 0.1164 | 0.90085 | 0.9119 |
P30838 | AL3A1 | Aldehyde dehydrogenase | 9 | 4.239 | 0.8126 | 1.1902 | 0.3191 |
P01042 | KNG1 | Kininogen-1 | 41 | 3.8584 | 0.1879 | 1.05845 | 0.8961 |
P63261 | ACTG | Actin, cytoplasmic 2 | 15 | 3.8377 | 0.2427 | 1.10115 | 0.2811 |
P19823 | ITIH2 | Inter-alpha-trypsin inhibitor heavy chain H2 | 8 | 3.65595 | 0.1392 | 1.0741 | 0.9467 |
P02647 | APOA1 | Apolipoprotein A-I | 78 | 3.59195 | 0.0914 | 1.11795 | 0.6642 |
P19652 | A1AG2 | Alpha-1-acid glycoprotein 2 | 24 | 3.4143 | 0.3822 | 1.1966 | 0.7947 |
P07225 | PROS | Vitamin K-dependent protein S | 2 | 3.1293 | 0.7689 | 1 | 0.9165 |
P25311 | ZA2G | Zinc-alpha-2-glycoprotein | 33 | 3.09115 | 0.0271 | 0.8365 | 0.2774 |
P43652 | AFAM | Afamin | 26 | 2.96685 | 0.2994 | 0.84275 | 0.1039 |
P80748 | LV302 | Ig lambda chain V-III region LOI | 6 | 2.94375 | 0.7735 | 0.88635 | 0.339 |
P00338 | LDHA | L-lactate dehydrogenase A chain | 6 | 2.818 | 0.6028 | 0.8556 | 0.956 |
P01024 | CO3 | Complement C3 | 139 | 2.7808 | 0.0006 | 1.02355 | 0.8534 |
P02750 | A2GL | Leucine-rich alpha-2-glycoprotein | 6 | 2.7016 | 0.0263 | 1.10115 | 0.7073 |
P02760 | AMBP | Protein AMBP | 13 | 2.63815 | 0.0112 | 0.8758 | 0.1804 |
P02675 | FIBB | Fibrinogen beta chain | 13 | 2.46095 | 0.023 | 0.8556 | 0.3175 |
P02774 | VTDB | Vitamin D-binding protein | 58 | 2.23515 | 0.2346 | 1.0093 | 0.37 |
P04196 | HRG | Histidine-rich glycoprotein | 27 | 2.048 | 0.9573 | 0.9315 | 0.5461 |
P00734 | THRB | Prothrombin | 20 | 2.02405 | 0.7763 | 0.91975 | 0.8888 |
P00747 | PLMN | Plasminogen | 32 | 1.9724 | 0.582 | 1.1067 | 0.3485 |
P05546 | HEP2 | Heparin cofactor 2 | 12 | 1.96475 | 0.8765 | 1.09015 | 0.5298 |
Q9HCQ7 | RFRP | FMRFamide-related peptides | 2 | 1.90125 | 0.2499 | 0.956 | 0.9658 |
P61626 | LYSC | Lysozyme C | 11 | 1.8574 | 0.3403 | 1.15915 | 0.5153 |
P04406 | G3P | Glyceraldehyde-3-phosphate dehydrogenase | 9 | 1.8478 | 0.9072 | 0.9731 | 0.1866 |
P01775 | HV314 | Ig heavy chain V-III region LAY | 2 | 1.81 | 0.5162 | 1.0636 | 0.8005 |
P00751 | CFAB | Complement factor B | 36 | 1.75395 | 0.4939 | 1.0333 | 0.3176 |
P10451 | OSTP | Osteopontin | 31 | 1.73075 | 0.5831 | 0.90085 | 0.6573 |
P01023 | A2MG | Alpha-2-macroglobulin | 67 | 1.70955 | 0.2094 | 1.00465 | 0.6274 |
P35749 | MYH11 | Myosin-11 | 2 | 1.7088 | 0.4505 | 1.10115 | 0.6608 |
P31025 | LCN1 | Lipocalin-1 | 7 | 1.61465 | 0.2414 | 1.14115 | 0.8803 |
P01861 | IGHG4 | Ig gamma-4 chain C region | 157 | 1.59305 | 0.8834 | 0.9688 | 0.9524 |
P01772 | HV311 | Ig heavy chain V-III region KOL | 5 | 1.5013 | 0.2508 | 1.0956 | 0.5357 |
Fold change: The average of 114:116 and 115:116, represents the differences between dry AMD and control group. Stability ratio: The average of 117:116 and 116:116, represents the stability of experimental.