Figure 5.

Acrylamide and withaferin A treatments have a reversable effect on dermal fibroblast migration and vimentin and actin fibres. (A) Corresponding plot showing the increased cell velocity of cells treated with acrylamide and decreased cell velosity of cells treated with withaferin A, which correlated with changed in vimentin amount. (B) The plot shows that cell velocity was not correlated to changes of F-actin amunt. Plots are presented using acrylamide 4 and 6 mM, and withaferin A 2.5 and 5 µM concentrations. The data of all concentrations are presented in Supplementary Figures S6 and S7.