Figure 3.
Estimated Mutation Rates under Different Rates of Genotype Error
The simulated mutation rate is 1.30 × 10−8 per base pair per meiosis and is indicated with the red dotted line. Point estimates (shapes) and 95% confidence intervals (bars) are shown. The maximum allele frequency threshold for the variants used for the mutation rate estimation is 3.75%. Two different simulation models, the homogeneous model (blue squares) and the admixed model (yellow circles) are assessed at error rates of 1 × 10−4, 5 × 10−4, and 1 × 10−3. Errors are simulated using the “unbiased” genotype error scheme (described in Material and Methods).