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Overall study design. Enrolled patients received both types of oxygen therapy, nasal cannula (NC) and high flow nasal cannula (HFNC). The sequence of oxygen therapy, NC followed by HFNC or HFNC followed by NC, was randomized with each type of oxygen therapy lasting for 20 minutes. Efficacy and subjective discomfort associated with each treatment were assessed at the end of each therapy type. ABGA: arterial blood gas analysis; EIT: electric impedance tomography.
