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A putative RNA switch element located in mammalian mitochondrial ATP8/ATP6 mRNA. A 46-nt overlapping region was uncovered in both ATP8 and ATP6 genes. This RNA fragment may form a putative stem-loop structure, which inhibits ribosome loading and translation initiation for ATP6 until the pioneering ATP8-translating ribosome unwinds it to mediate the coordinated translation of ATP8/ATP6 mRNA and maintain 1:1 stoichiometric ratio of both proteins.
