Hematological Parameters and Anemia Prevalence in 16p11.2 BP4-BP5 CNV Carriers
(A) Red blood cell distribution width (RDW), mean reticulocyte volume (MRV), platelet count (PLTc), mean platelet volume (MPV), and platelet crit (PLTcrit) in 16p11.2 deletion and duplication carriers and control individuals in the UK Biobank (UKB). Beta and p values of linear models and p-values of paired t-tests are shown.
(B) Prevalence of anemia in 379,385 control individuals and 89 16p11.2 deletion carriers in the UKB (top) and 83 16p11.2 deletion carriers in the Simons Variation in Individuals Project (SVIP) and European cohorts stratified by BOLA2 copy number (bottom).