Genetic Heterogeneity of Tumors from PTC-Affected Subjects
The total number of coding and noncoding mutations (top) and copy-number variants (bottom) detected in each tumor region, according to relapse, type of tissue (R, relapsed tissue; p, primary tissue), tumor stage, age, number of tissues, and HIF-1α immunohistochemical staining (IHC), with proportions of clonal and subclonal somatic variants. Grey areas correspond with a lack of mutations/copy number variants.