Figure 6.

Heterogeneity of Driver Mutations in PTC

Driver alterations detected for each tumor. All genes containing driver alterations across the cohort are included. The color represents the clonal status (blue, clonal; red, subclonal). Number of driver alterations identified across tumors (top) and the barplots to the right are proportion of variants found as clonal/subclonal in relapsed tissue (R), primary relapse (P; green), and primary non-relapse (P; pink) tissues for each gene, along with total count of driver alterations. Pie charts represent the overall proportion of subclonal driver events per category. Treatment intervals are in days, from diagnosis to surgical intervention.