Table 5.
Generalized linear regression analysis showing the associations between neonatal birth weight and maternal measures. Using the Akaike information criteria (AIC), model 2 was selected because it has the smallest AIC value
| Maternal variables | Univariate (unadjusted) |
1Full model (n = 138) AIC = 2071.32 |
2Model 2 (n = 138) AIC = 2053.40 |
3Model 3 (n = 138) AIC = 2066.53 |
||||
|---|---|---|---|---|---|---|---|---|
| β (95% CI) | P-value | β (95% CI) | P-value | β (95% CI) | P-value | β (95% CI) | P-value | |
| Height (cm) | 17.42 (5.82, 29.01) | < 0.01 | 20.32 (5.65, 34.99) | 0.01 | 14.97 (2.51, 27.43) | 0.02 | 13.1 (0.76, 25.42) | 0.04 |
| Weight (kg) | 11.15 (3.20, 19.09) | 0.01 | 3.80 (−6.84, 14.44) | 0.48 | 6.86 (−1.62, 15.35) | 0.11 | 7.75 (−0.67, 16.16) | 0.07 |
| Homocysteine (μmol/l) | −26.67 (−54.78, 1.44) | 0.06 | −32.99 (− 62.03, −3.95) | 0.03 | −33.26 (− 60.21, − 6.31) | 0.02 | ||
| 2hPG (mmol/l) | 44.93 (− 15.76, 105.62) | 0.15 | 51.54 (− 11.97, 115.06) | 0.11 | 51.31 (−8.00, 110.63) | 0.09 | ||
| Triglycerides (mg/dl) | −0.93 (−2.21, 0.34) | 0.15 | −0.96 (−2.48, 0.56) | 0.22 | −1.09 (− 2.31, 0.14) | 0.08 | ||
| Hemoglobin | −24.88 (− 80.13, 30.38) | 0.38 | −5.75 (−68.68, 57.18) | 0.86 | ||||
| FPG (mmol/l) | 70.77 (−70.28, 211.82) | 0.32 | 46.92 (−97.80, 191.65) | 0.53 | ||||
| Insulin (μIU/ml) | 7.38 (−6.76, 21.51) | 0.30 | 11.07 (−4.59, 26.74) | 0.17 | ||||
| Cholesterol (mg/dl) | −0.43 (−3.30, 2.44) | 0.77 | −0.94 (− 4.36, 2.48) | 0.59 | ||||
| HDL-C (mg/dl) | 5.59 (−4.88, 16.06) | 0.29 | 6.01 (−5.43, 17.44) | 0.30 | ||||
| Vitamin D (nmol/l) | −0.96 (− 5.27, 3.35) | 0.66 | −0.45 (− 5.01, 4.11) | 0.85 | ||||
| Vitamin B12 (pg/ml) | 0.10 (−0.40, 0.60) | 0.69 | −0.07 (− 0.60, 0.46) | 0.80 | ||||
| Ferritin (ng/ml) | 0.56 (−0.98, 2.11) | 0.47 | 0.45 (−1.15, 2.04) | 0.58 | ||||
| Folate (ng/ml) | −2.72 (−10.88, 5.43) | 0.51 | −0.51 (−9.00, 7.97) | 0.91 | ||||
| Age (years) | 12.69 (−10.50, 35.88) | 0.28 | −6.08 (−32.70, 20.55) | 0.66 | ||||
| Gestational age in weeks | −11.83 (−55.64, 31.98) | 0.60 | −24.20 (−70.14, 21.74) | 0.30 | ||||
| BMI (kg/m2) | 16.28 (−3.01, 35.58) | 0.10 | ||||||
| LDL-C (mg/dl) | −0.27 (−3.29, 2.75) | 0.86 | ||||||
| HOMA-IR | 41.48 (−18.76, 101.72) | 0.18 | ||||||
1Model 1 is adjusted for all maternal variables 2Model 2 was fitted by selecting variables with P ≤ 0.2 from the univariate analysis
3Model 3 was fitted by selecting variables with P ≤ 0.05 from the univariate analysis
Abbreviation: 2hPG 2 h plasma glucose, FPG fasting plasma glucose, HDL-C high density lipoprotein cholesterol, BMI body mass index, LDL-C low density lipoprotein cholesterol, HOMA-IR homeostasis model assessment of insulin resistance