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The figure showed the histopathological findings in H&E (Panels A and B). Necrotic tissue and inflammatory infiltrate are observed along with unstained long filaments corresponding to Pythium insidiosum hyphae and some eosinophils (arrows). Panels C and D are Gomori Methenamine-Silver (GMS) stains showing the presence of transversally and longitudinal P. insidiosum hyphae penetrating deep in the subcutaneous tissues. (Panels A and C= 10X; Panels B and D= 50X).
