TABLE 2.

Statistical analysis for interaction (time × vagal-type) according (Figures 2, 3).

Repeated measures ANOVA (N = 16) [4 × 2 design (time × vagal-type)]† logRSArr [ms]		Vagal-type				Effects time vagal-type	F	P significance	${\mathrm{\eta }}_{\text{p}}^2$
		Strong vagal		Weak vagal
		activity (n = 8)		activity (n = 8)
		mean	SD	mean	SD
Sleep	Pre-operative	1281	0,088	1022	0,139
	Peri-operativ	1,114	0,151	0,927	0,145	Time	4,203	0.022∗	0,231
	Rehabilitation	1246	0,110	0,966	0,248	Vagal-type	13,803	0.002∗∗	0,496
	Long-term recovery	1287	0,120	0,951	0,279
	Overall	1,232	0,083	0,967	0,184	Interaction	1,287	0.292	0,084
Wake	Pre-operative	1,007	0,177	0,767	0,079
	Peri-operativ	0,907	0,111	0,709	0,192	Time	2,224	0.099(*)	0,137
	Rehabilitation	1,007	0,155	0,675	0,201	Vagal-type	14,528	0.002∗∗	0,509
	Long-term recovery	1,007	0,112	0,757	0,200
	Overall	0,982	0,118	0,727	0,148	Interaction	1,234	0.306	0,082
Mean-24 h	Pre-operative†	1,097	0,125	0,863	0,066
	Peri-operativ	0,986	0,109	0,783	0,162	Time	3,273	0.048∗	0,190
	Rehabilitation	1,095	0,118	0,775	0,190	Vagal-type	17,151	0.001∗∗	0,551
	Long-term recovery	1,089	0,111	0,844	0,222
	Overall	1,067	0,090	0,816	0,146	Interaction	1,141	0.336	0,075
	Time					Time	4,432	0.042∗	0,869
MANOVA	Vagal-typ					Vagal-type	5,208	0.016∗	0,566
	Interaction (Time × vagal-type)					Interaction	5,900	0.021∗	0,898

^†A median split of pre-operative vagal activity was used to classify into vagal-types with strong of weak vagal activity (cut-off value: 0.9654). This classification was also used for Figure 5. ^∗p < 0.05 and ^∗∗p < 0.01.