Table 2.

Clinical and pathological parameters of colorectal carcinomas with double somatic mismatch repair gene mutation/alteration.

Case ID	Age	Gender	Tumor location	Dominant histology	Histologic grade	Tumor-infiltrating-lymphocytes / high-power-field	Peritumoral lymphoid aggregates	pT (or ypT*)	pN	pM
1	80	Female	Ascending	Conventional	Poorly differentiated	2	5	3	2b	0
2	65	Male	Ascending	Medullary		51	11	3	1b	0
3	52	Female	Cecum	Conventional	Moderately differentiated	7	2	4b	1a	0
4	68	Female	Left colon	Conventional	Moderately differentiated	7	0	4a	1c	0
5	48	Male	Ascending	Conventional	Poorly differentiated	3	3	4a	2a	0
6	59	Female	Cecum	Conventional	Moderate	5	7	4a	2a	0
7	60	Male	Sigmoid	Conventional	Poorly differentiated	1	1	3	0	0
8	46	Male	Transverse	Mucinous	Moderately differentiated	7	5	3	0	1
9	35	Female	Transverse	Mucinous	Moderately differentiated	1	4	4a	2b	0
10	53	Male	Sigmoid	Mucinous	Moderately differentiated	19	6	3	0	0
11	61	Male	Ascending	Signet Ring	Poorly differentiated	0	13	3	1b	0
12	53	Male	Cecum	Conventional	Poorly differentiated	32	6	3	0	0
13	41	Male	Rectum	Conventional	Moderately differentiated	4	0	2*	1a	0
14	31	Male	Ascending	Conventional	Moderately differentiated	3	15	3	2a	0
15	61	Male	Ascending	Conventional	Moderately differentiated	2	4	2	0	0

^*ypT. Case underwent standard neoadjuvant treatment.