Morphometric changes in the brainstem A, Morphometric brainstem alterations in ALS patients compared to healthy controls at p < .05 TFCE FWE corrected for age, gender, education and TIV. B, Morphometric brainstem alterations in ALS patients compared to disease controls (FTD) at p < .05 TFCE FWE corrected for age, gender, education and TIV. C, Morphometric brainstem alterations in ALS patients compared to PLS patients at p < .05 TFCE FWE corrected for age, gender, education and TIV. Statistical maps are presented in MNI space, MNI coordinates are provided under each view, and the brainstem mask is presented as a white underlay. Radiological convention is used; Lt – Left, Rt – Right.