Table 1.
Respondent and patient characteristics
| Parameter | Canada | France | Germany | Italy | Spain | UK | USA | Pooled |
|---|---|---|---|---|---|---|---|---|
| Number of respondents | 30 | 30 | 30 | 30 | 30 | 30 | 50 | 230 |
| Specialty, n (%) | ||||||||
| Hematologist/Oncologist | 16 (53) | 21 (70) | 23 (77) | 21 (70) | 19 (63) | 23 (77) | 25 (50) | 148 (64) |
| Immunologist | 5 (17) | 1 (3) | 1 (3) | 3 (10) | 9 (30)a | 3 (10) | 10 (20) | 32 (14) |
| Internal medicine | 3 (10) | 5 (17) | 2 (7) | 3 (10) | 1 (3) | 2 (7) | 10 (20) | 26 (11) |
| Pediatrician | 6 (20) | 2 (7) | 4 (13) | 3 (10) | 1 (3) | 1 (3) | 5 (10) | 22 (10) |
| Other | 0 (0) | 1 (3) | 0 (0) | 0 (0) | 0 (0) | 1 (3) | 0 (0) | 2 (1) |
| Clinical experience, n (%) | ||||||||
| <5 y | 3 (10) | 1 (3) | 0 (0) | 5 (17) | 3 (10) | 1 (3) | 5 (10) | 18 (8) |
| 5‐15 y | 16 (53) | 12 (40) | 16 (53) | 11 (37) | 17 (57) | 21 (70) | 24 (48) | 117 (51) |
| >15 y | 11 (37) | 17 (57) | 14 (47) | 14 (47) | 10 (33) | 8 (27) | 21 (42) | 95 (41) |
| Directly responsible for diagnosis of SID and prescription of IgG, n (%) | 24 (80) | 29 (97) | 29 (97) | 28 (93) | 26 (87) | 27 (90) | 45 (90) | 208 (90) |
| Number of patients cared for per respondent, n, median | ||||||||
| CLL | 15 | 40 | 50 | 30 | 23 | 35 | 20 | 213 |
| MM | 15 | 39 | 46 | 45 | 21 | 38 | 15 | 219 |
| NHL | 10 | 33 | 60 | 50 | 33 | 31 | 25 | 242 |
| Other lymphoproliferative diseases | 10 | 20 | 23 | 35 | 20 | 18 | 15 | 141 |
| All indications | 50 | 132 | 179 | 160 | 97 | 122 | 75 | 815 |
| Patients cared for with severe or recurring infections, n (% patients) | ||||||||
| CLL | 398 (34) | 335 (28) | 655 (35) | 730 (29) | 461 (38) | 280 (21) | 496 (25) | 3355 (30) |
| MM | 263 (26) | 371 (30) | 454 (29) | 521 (25) | 314 (31) | 292 (23) | 489 (26) | 2704 (27) |
| NHL | 300 (26) | 341 (26) | 677 (27) | 531 (27) | 326 (26) | 219 (18) | 400 (20) | 2794 (24) |
| Other lymphoproliferative diseases | 193 (27) | 241 (24) | 399 (24) | 424 (27) | 311 (27) | 135 (19) | 368 (22) | 2071 (24) |
| Patients cared for with hypogammaglobulinemia (IgG < 4 g/L), n (% of patients) | ||||||||
| CLL | 369 (32) | 433 (36) | 631 (34) | 911 (36) | 438 (36) | 366 (27) | 609 (31) | 3721 (33) |
| MM | 241 (24) | 446 (36) | 403 (25) | 720 (35) | 339 (34) | 405 (32) | 505 (27) | 3043 (30) |
| NHL | 247 (22) | 362 (28) | 593 (24) | 490 (25) | 347 (28) | 173 (14) | 478 (24) | 2669 (23) |
| Other lymphoproliferative diseases | 196 (28) | 331 (32) | 365 (22) | 379 (24) | 319 (28) | 112 (16) | 396 (23) | 2086 (25) |
CLL, chronic lymphocytic leukemia; MM, multiple myeloma; NHL, non‐Hodgkin lymphoma.
a
Includes four physicians classified as allergists/immunologists.