Table 1. Clinical characteristics of patients.
Characteristics | Prostatectomy discovery cohort (n = 63) | ||
---|---|---|---|
BCR (n = 21) | Non-BCR (n = 42) | p value | |
Time from RP to BCR1 (median), months | 19.4 (2.5–98.6) | ||
Time from RP to last PSA follow-up, months | 97.4 (58.1–166.8) | ||
Range of surgery year | 1998–2008 | 1997–2007 | |
Age | |||
Median (IQR) | 58.3 (45–70) | 56.4 (40–75) | 0.26 |
< 50 | 3 (14%) | 11 (26%) | |
50–60 | 10 (48%) | 17 (41%) | |
60–70 | 7 (33%) | 11 (26%) | |
> 70 | 1 (5%) | 3 (7%) | |
Race | |||
American Caucasian | 14 (67%) | 27 (64%) | |
American African | 6 (28%) | 13 (31%) | |
Hispanic/Other | 1 (5%) | 2 (5%) | |
Clinical tumor stage | |||
T1 | 12 (57%) | 24 (57%) | |
T2 | 7 (33%) | 17 (40%) | |
Unknown | 2 (10%) | 1 (3%) | |
Pre-surgery PSA | |||
Median (IQR) | 4.7 (1.8–13.6) | 4.7 (0.7–14.2) | 0.74 |
BMI | |||
Median (IQR) | 27 (19–34) | 26 (16–33) | 0.11 |
Prostate weight | |||
Median (IQR) | 39.5 (23.4–48.4) | 36.6 (22.3–63.7) | 0.46 |
Signs of further progression | |||
positive margins | Negative | Negative | |
Extra-capsular extension | Negative | Negative | |
Seminal vesicle invasion | Negative | Negative | |
Pathology GS | |||
≤ 6 (3+3) | 12 (57%) | 30 (71%) | |
7 (3+4) | 9 (43%) | 12 (29%) | |
Pathology tumor stage | |||
T2 | 21 (100%) | 40 (95%) | |
T3A | 0 (0%) | 2 (5%) |
BCR = Biochemical recurrence, RP = Radical prostatectomy, IQR = interquartile range, PSA = Prostate-specific antigen, GS = Gleason score.