Table 2.
Gene | Target | Rel. position | NC_002951 | Variant AA | 17, 47 | Isolates with variants | |
---|---|---|---|---|---|---|---|
80, 86 | 81, 87, 110 | ||||||
agrA | SACOL2026 | 409 | G | D → Y | G | T | T |
agrA | SACOL2026 | 520 | C | H → Y | C | C | T |
Two subsequent non-synonymous SNPs were discovered in agrA of the clinical S. aureus isolates. Nuclease and RNAIII activity inversely correlated with the presence of both mutations.