Table 2. .
Target pathway | Potential radiopharmaceuticals |
---|---|
Tumour hypoxia |
18F-MISO 18F-FAZA 18F-HX4 60/61/62/64Cu-ATSM |
Protein and cell membrane synthesis |
11C or 18F-choline 11C-acetate |
Transporter-targeted agents |
11C-MET 18F-FET 18F-FACBC |
Receptor-targeted agents |
68Ga-DOTATOC/DOTANOC/DOTATATE 68Ga-pentixafor |
Protein-targeted agents |
68Ga-PSMA 18F-FLT |
11C-MET, 11C-L-methyl-methionine; 60/61/62/64Cu-ATSM, 60/61/62/64copper(II)-diacetyl-bis(N4-methylthiosemicarbazone); 18F-FACBC, anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid; 18F-FAZA, 18F-fluoroazomycin; 18F-FET, 18F-fluoroethyltyrosine; 18F-FLT, 18F-fluorothymidine; 18F-HX4, 18F-flortanidazole; 18F-MISO, 18F-fluoromisonidazole;68Ga-PSMA, 68Ga-prostate-specific membrane antigen.