Table 3.
Subgroup analyses
| Subgroup | Patients | Odds ratio | 95% CI | P value | |
|---|---|---|---|---|---|
| With SCL (n = 9) | Without SCL (n = 88) | ||||
| Age ≥ median (62 y) | 5 (56) | 48 (55) | 1.04 | 0.21‐5.61 | 1.00 |
| Sex, male | 7 (78) | 59 (67) | 1.72 | 0.30‐17.9 | 0.71 |
| Hypertension | 7 (78) | 60 (68) | 1.63 | 0.28‐17.0 | 0.72 |
| CHADS2‐VASc score ≥3 | 2 (22) | 23 (26) | 0.81 | 0.08‐4.68 | 1.00 |
| Heparin bridging | 6 (67) | 54 (64), n = 85 | 1.15 | 0.23‐7.58 | 1.00 |
| Novel anticoagulant preablation and postablation | 4 (44) | 36 (42), n = 85 | 1.08 | 0.20‐5.45 | 1.00 |
| Additional lesions performed | 1 (11) | 16 (18) | 0.56 | 0.01‐4.76 | 1.00 |
| Method of left atrial access = double puncture | 6 (67) | 70 (80), n = 87 | 0.49 | 0.09‐3.33 | 0.39 |
| Mean ACT < median (311 s) | 5 (56) | 38 (49), n = 78 | 1.32 | 0.26‐7.13 | 0.74 |
| Minimum ACT (<250 s) | 7 (78) | 41 (47) | 4.01 | 0.70‐41.1 | 0.09 |
| INR at ablation out of range 2‐3 | 1 (50), n = 2 | 3 (18), n = 17 | 4.67 | 0.04‐391.7 | 0.39 |
| INR at postablation <2 | 1 (33), n = 3 | 6 (27), n = 22 | 1.33 | 0.02‐30.0 | 1.00 |
| Electrical cardioversion performed | 1 (11) | 15 (17) | 0.61 | 0.01‐5.17 | 1.00 |
| Procedure time > median (120 min) | 5 (56) | 44 (50) | 1.25 | 0.25‐6.72 | 1.00 |
| Patient suffers tamponade a | 1 (11) | 2 (2) | 5.38 | 0.08‐111.1 | 0.26 |
Abbreviations: ACT, activated clotting time; CI, confidence interval; INR, international normalized ratio; SCL, silent cerebral lesion.
a
One patient with a pericardial tamponade did not undergo MRI scanning.