Table 2.
Observed and expected numbers of cancer cases and standardized incidence ratios (SIR) with 95% confidence intervals (CI) among Finnish NF1 patients aged <20 years by cancer location
| Location | ICD‐10 codes | Expected | Observed | SIR | 95% CI |
|---|---|---|---|---|---|
| Brain, CNS | C70‐C72 | 0.39 | 45 | 115.7 | 86.4 to 155.0 |
| non‐OPG tumors in brain, CNS | C70‐C72 | 0.39 | 23 | 59.1 | 39.3 to 89.0 |
| Peripheral nerves and autonomic nervous system | C47 | 0.03 | 8 | 271.7 | 135.9 to 543.2 |
| Soft tissues | C48‐C49 | 0.06 | 2 | 33.8 | 8.5 to 135.3 |
| Bone | C40‐C41 | 0.04 | 1 | 24.7 | 3.5 to 175.6 |
Abbreviations: CNS, central nervous system; ICD‐10, International classification of diseases, 10th edition; OPG, optic pathway glioma.