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. 2019 Apr 7;61(5):337–342. doi: 10.1111/dgd.12604

Figure 2.

Figure 2

Sas‐PTP10D drives elimination of polarity‐deficient cells. (a) Jun N‐terminal kinase (JNK) signaling induces elimination of polarity‐deficient cells by SAS/PTP10D‐mediated inhibition of EGFR signaling. (b) In the absence of SAS/PTP10D system, EGFR signaling switches JNK signaling from cell death to overgrowth. See text for details