Table 2.
Effects of histopathological parameters and the Ki67 PI on survival: univariate analyses
| Parameter | Distribution | Total | Hazard ratio (95%CI) | P value |
|---|---|---|---|---|
| Decreased reticulin fibre density | 85 (19‐100) % | 50 | 1.018 (0.987‐1.051) | 0.257 |
| Clear/vacuolated cytoplasm | 48 (5‐96) % | 50 | 1.023 (1.004‐1.043) | 0.020* |
| Extramedullary haematopoiesis | 37 no, 13 yes | 50 | 0.882 (0.284‐2.737) | 0.828 |
| Necrosis | 30 no, 20 yes | 50 | 3.495 (1.336‐9.141) | 0.011* |
| Ki67 PI | 3 (0‐22) % | 50 | 1.174 (1.065‐1.295) | 0.001* |
Abbreviation: PI, proliferation index.
Univariate analyses performed with the Cox proportional hazards model. Distribution is indicated in categories for categorical variables, and in median (with the range in parentheses) for continuous variables. Total indicates the total number of dogs for which this parameter was known. Hazard ratio (with the 95% confidence interval in parentheses) indicates the hazard of the second category compared to the first in case of categorical parameters, and the hazard per stated unit in case of continuous variables. Significant P values are indicated in italic with an asterisk.