Table 5.
Association between characteristics at diagnosis and the implementation of invasive treatments for obstruction of Budd–Chiari syndrome as potential predictors of invasive treatments: 2015 survey, Japan
| Characteristic | Invasive treatments | Univariate | Multivariate† | |
|---|---|---|---|---|
| n/N (%) | OR (95% CI) | OR (95% CI) | ||
| Total | 50/109 (46) | |||
| Sex | Male | 29/65 (45) | 1.00 | 1.00 |
| Female | 21/44 (48) | 1.13 (0.53–2.44) | 1.14 (0.49–2.65) | |
| Confirmation of diagnosis | Not confirmed | 3/15 (20) | 1.00 | 1.00 |
| Confirmed | 46/93 (49) | 3.92 (1.04–14.8) | 3.45 (0.87–13.7) | |
| Age at diagnosis, years | <40 | 21/51 (49) | 1.00 | 1.00 |
| 40+ | 18/47 (38) | 0.65 (0.29–1.44) | 0.60 (0.26–1.39) | |
| Duration from symptom onset, years | <1.0 | 17/46 (37) | 1.00 | 1.00 |
| 1.0+ | 14/18 (78) | 5.97 (1.69–21.1) | 9.30 (2.14–40.4) | |
| Clinical symptoms at diagnosis | ||||
| Ascites | Absent | 22/57 (39) | 1.00 | 1.00 |
| Present | 24/41 (59) | 2.25 (0.99–5.09) | 2.60 (1.08–6.27) | |
| Splenomegaly | Absent | 9/34 (26) | 1.00 | 1.00 |
| Present | 30/58 (52) | 2.98 (1.19–7.47) | 2.63 (0.96–7.19) | |
| Anemia | Absent | 21/53 (40) | 1.00 | 1.00 |
| Present | 18/34 (53) | 1.71 (0.72–4.09) | 2.60 (0.88–7.70) | |
| Laboratory data | ||||
| Albumin, g/dL | <4.1 | 26/51 (51) | 1.99 (0.82–4.84) | 2.37 (0.85–6.60) |
| 4.1+ | 12/35 (34) | 1.00 | 1.00 | |
| Type of obstructive pattern | ||||
| Inferior vena cava (isolated) | 6/16 (38) | 1.00 | 1.00 | |
| Hepatic vein (isolated) | 5/17 (29) | 0.69 (0.16–2.97) | 0.42 (0.08–2.32) | |
| Both inferior vena cava and hepatic vein | 26/44 (59) | 2.41 (0.74–7.81) | 1.84 (0.46–7.38) | |
†
Adjusted for sex, confirmation of diagnosis, and age at diagnosis.
CI, confidence interval; OR, odds ratio.