Table 2.
Factors causing variations in tRNA modifications
| System description | Growth phase | Growth medium | Growth conditions | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Organisma | tRNA | Modification | Exponential phase | Stationary phase | Growth rate | Rich medium | Glucose salt medium | Aerobic growth | Anaerobic growth | Temperature | Tumors | References |
| Bs | + b | ++ | 114 | |||||||||
| Bs | tRNATyr | i6A37 | ms2i6A37 | 115 | ||||||||
| Ec | ms2i6A37 | ● | 116 | |||||||||
| Ec | Q34 | ● | 117 | |||||||||
| Ec | tRNALeu 1, tRNAGly 2&3, tRNAPro 1 | s4U8 | ● | 118 | ||||||||
| Bs | tRNAPhe | Gm34 | G34 | 119 | ||||||||
| Bs | tRNAPhe | ms2i6A37 | i6A37 | 119 | ||||||||
| St | Q34 | oQ34 | 120 | |||||||||
| St | ms2io6A37 | ms2i6A37 | 121 | |||||||||
| Tt, Mb, Sh, Sc | ● | 12, 112, 113, 122, 123 | ||||||||||
| Hs | tRNAPhe | yW37 | – c | 124 | ||||||||
| Hs | tRNAAsp | Q34 | – c | 125 | ||||||||
a
Bs: Bacillus subtilis; Ec: Escherichia coli; St: Salmonella typhimurium; Tt: Thermus thermophilus; Mb: Methanococcoides burtonii; Sh: Stetteria hydrogenophila; Sc: Saccharomyces cerevisiae; Hs: Human.
b
Hypomodified in the exponential phase compared to the stationary phase.
c
Hypomodified in tumors.