Table 4.

Subjective and objective scar assessment

	Flaminal® Forte			Flamazine®
	No. (valid)	Median	Range	No. (valid)	Median	Range	p *
Subjective scar assessment
POSAS patient score†
General impression
3 months post burn	35	5	1–10	42	4	1–10	0.70
6 months post burn	34	4	1–10	41	3	1–10	0.30
12 months post burn	35	3	1–10	38	2	1–10	0.09
POSAS observer score⊥
General impression
3 months post burn	35	5	1–10	42	4	1–10	0.70
6 months post burn	34	4	1–10	41	3	1–10	0.30
12 months post burn	35	3	1–10	38	2	1–10	0.09
Objective scar assessment
Scar color (erythema)¶ , ††
3 months post burn	35	11.0	0.24–27.9	42	9.5	0.66–37.1	0.65
6 months post burn	35	5.8	0–28.3	41	5.3	0.43–27.7	0.37
12 months post burn	35	3.2	0.07–17.4	35	3.3	0.5–10.5	0.24
Scar pigmentation (melanin)** , ††
3 months post burn	35	6.7	0.3–28.5	42	8.0	0.1–25.0	0.53
6 months post burn	35	3.3	0.4–15.0	35	4.2	0.07–12.8	0.84
12 months post burn	39	3.7	0–17.4	39	2.6	0.3–18.4	0.59
Scar extension (Uf)⊥⊥ , ***
3 months post burn	35	0.70	0.35–1.58	40	0.70	1.40–1.60	0.86
6 months post burn	35	0.73	0.20–1.28	41	0.74	0.06–1.31	0.86
12 months post burn	35	0.84	0.29–1.35	40	0.79	0.47–1.60	0.75
Scar elasticity (Ue)¶¶ , ***
3 months post burn	35	0.62	0.22–1.36	35	0.60	0.20–1.94	0.50
6 months post burn	35	0.62	0.09–1.27	41	0.60	0.35–1.33	0.86
12 months post burn	35	0.78	0.19–1.35	40	0.70	0.36–1.57	0.71

^* Mann–Whitney U test.

^† Patient and Observer Scar Assessment Scale (POSAS) general impression score provided by the patient.

^⊥ Patient and Observer Scar Assessment Scale (POSAS) general impression score provided by the observer.

^¶ Scar color (Erythema) obtained by the DermaSpectrometer®.

^** Scar pigmentation (Melanin) obtained by the DermaSpectrometer®.

^†† Values were calculated as absolute difference between scar tissue and the nonaffected skin.

^⊥⊥ Scar extension results (Uf) obtained by the Cutometer®.

^¶¶ Scar elasticity (Ue) obtained by the Cutometer®.

^*** Values represent the ratio between scar tissue and nonaffected skin.