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. 2019 Apr 22;33(5):589–600. doi: 10.1111/fcp.12463

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© 2019 The Authors. Fundamental & Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of Société Française de Pharmacologie et de Thérapeutique

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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(a) Reporting odds ratios of hypersensitivity reactions for any NSAIDs according to cyclo‐oxygenase selectivity with coxibs as a reference group. (b) Reporting odds ratios of hypersensitivity reactions of any NSAIDs according to chemical groups with coxibs as a reference group. (c) Reporting odds ratios of hypersensitivity reactions for any NSAIDs according to the presence/absence of sulfonamide groups with nonsulfonamide NSAIDs as a reference group.

AADs, acetic acid derivatives and related substances; COX‐2, cyclo‐oxygenase‐2; NA, not applicable; NSAIDs, nonsteroidal anti‐inflammatory drugs; PADs, propionic acid derivatives; RORs, reporting odds ratios.

*Statistically significant (P < 0.05).