Table 3.
On‐demand (n = 6) | Prophylaxis (Combined)a (n = 17) | |
---|---|---|
Bleeds treated with: | (N = 432 bleeds) | (N = 67 bleeds) |
≤2 infusions, n (%) | 420 (97.2) | 61 (91.0) |
Not treated, n (%) | 2 (0.5) | 4 (6.0) |
Median (range) injections per bleed | 1.0 (0‒3) | 1.0 (0‒4) |
Median (range) nominal dose per infusion, IU/kg/infusion | 21.4 (15.0‒23.5) | 27.3 (23.5‒41.6) |
Median (range) nominal dose per year, IU/kg/y | 1642.3 (1225‒2599) | 120.6 (47‒608) |
Combined prophylaxis includes all patients who received BAY 81‐8973 prophylaxis in LEOPOLD II.